mice," genetically engineered by Howard Hughes Medical Institute researchers,
can run twice as far as their unaltered buddies. Previously, the only known
way to increase endurance was through training.
… To perform the genetic enhancement on the mice, researchers injected
a human version of a protein called PPAR-delta attached to a short DNA sequence.
The injection permanently incorporated enhanced PPAR-delta production into
the mice’ genomes. The change is transgenic, meaning the mice will pass down
the trait to future generations.
To explore how traits can be passed to future mice generations, please check
out our Gizmo on this topic: Mouse
In the Mouse Genetics Gizmo, you can try the similar types of experiments as
those used by the researchers at the Howard Hughes Medical Institute to study
the principles of dominant and recessive genes.